Tim Radford, science editor 

How to save lives with your screensaver

Forget cyberaquariums, starry nights or pictures of Elvis. Oxford scientists are appealing for computer users to donate screensaver time in a search for potential cancer cures.
  
  


Forget cyberaquariums, starry nights or pictures of Elvis. Oxford scientists are appealing for computer users to donate screensaver time in a search for potential cancer cures.

Oxford University's department of chemistry hopes thousands of people who leave their computers on when not in use will install a different kind of screensaver that can do molecular research.

To neutralise a virus or block a tumour, a molecule of a drug has to lock into a human protein.

Scientists can test the drugs as 3-D shapes on a screen. The catch is that there are 250m molecules to sift.

"To test those crudely, even using supercomputers, would take more than a lifetime," said Professor Graham Richards of the centre for drug discovery at Oxford. "But if you string together a million personal computers you would have enormous computing power."

Oxford scientists have developed a computer tool called Think, and will send anyone who volunteers for the scheme an initial cyberpackage of 100 molecules and a cyberprotein known to be involved in cancer.

Office workers use only about 20% of the power in their computers. The rest could be harnessed for cancer research, with a self-organising programme which quietly sends back to Oxford those molecules that look promising.

 

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