Rachel Weisz and Rachel McAdams are to star in a big screen adaptation of Naomi Alderman’s acclaimed novel Disobedience.

The book, which was published in 2006, is set in north west London and features the return to the Orthodox Jewish family home of Ronit (Weisz) following the death of her father. She then rekindles a romance with her best friend (McAdams), who is now married to her cousin.

Chilean film-maker Sebastian Lelio – whose 2013 portrait of a middle-aged woman, Gloria, won many fans – will direct.

McAdams will next be seen in Marvel’s Doctor Strange opposite Benedict Cumberbatch and Tilda Swinton, while Weisz stars in Denial, as well as featuring in The Light Between Oceans.

Both actors were involved in Terrence Malick’s 2013 drama To the Wonder, although Weisz’s scenes were cut from the final edit.